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mas but not in non-seminomas, compared to standard peri-tumoural tissues. Evaluation of mRNA by RT-PCR revealed that both JKT-1 and NCCIT cells expressed GPER. These outcomes had been confirmed by Western blotting, which revealed the expected 42-kDa band for the GPER protein. The JKT-1 cells showed drastically larger GPER protein levels than the NCCIT cells, whereas GPER mRNA expression was greate
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eral neuropathy occurred in 25 individuals; in eight, neuropathy was severe. Hypothyroidism was widespread, with practically one particular third with the patients getting altered thyroid function tests, at a median time of 16 weeks on DR-TB therapy. Psychiatric AE had been also widespread and occurred early in treatment; almost 1 third of sufferers experienced psychiatric disturbances and in eigh